What I-Bind Does

Repeated use of diluted I-Bind lays down a protective polymer that complexes irreversibly with Radioactive Iodine and F-18 for easy removal with simple washing. We provide a “High Volume Area Sprayer” for this purpose.

A “Hot-Spot Foam Sprayer” is provided to target spills and other contaminated surfaces. I-Bind traps RadioIodine and F-18 keeping them from becoming airborne in the form of a radioactive gas which can be breathed by Laboratory Personal and can condense on Lab surfaces where it is not anticipated to be.

Targeted Applications for I-Bind. . .

Gamma Counter CleanUp: I-Bind contains no EDTA or other chelators that can attack delicate detectors. Other cleaners contain compounds that attack the thin aluminum housing that protects the sodium iodide crystals used in Gamma Counters. When the aluminum wells become pitted, the hygroscopic sodium iodide inside absorbs water from the air, turning the crystal yellow. This condition is marked by a precipitous drop in counting efficiency and the detector must be replaced at considerable expense.

Thyroid Ablation CleanUp and RadioIodination Contamination Control: Both of these procedures involve the use of elemental RadioIodine which is extremely volatile, forming a hazardous gas if not checked. As early in the processes as possible components and containers where RadioIodine may be found should be treated with diluted I-Bind to remove the threat of radioactive gases and effect full containment.

General Rules for Handling Radioactive Materials, compliance methods: The predominant precept for achieving “ALARA”, “As Low As Reasonably Achievable” risks for exposure to ionizing radiation in the Lab working with exempt amounts of I-125 centers around limiting the potential ingestion of RadioIodine and less about limiting exposure to the dose effects of RadioIodine stored in the lab.

The single most effective way to accomplish this involves the routine use of diluted I-Bind on all the surfaces of the RIA Lab. Continued use results in a buildup of a film of the protective polymer that traps I-125 and allows it to be safely washed away with little or no residual radioactivity.

In Nuclear Medicine Labs the classical decontamination agents intended for Tc-99m, Fe-59, Cr-51, In-111 and Ga-68 were designed with harsh chemicals and chelators to digest and bind these radionuclides. When dealing with radionuclides that are halogens, like I-131, I-125, I-123 and F-18 there is the possibility that radioactive gases of these radionuclides are liberated from the spill using the classical decontamination agents. These halides are not bound by conventional chelators.

I-Bind was designed to specifically avoid producing these dangerous gases from the RadioHalides, initially for the RadioIodines alone, but now it has been shown that there is similar protection with F-18. If allowed, the I-Bind complex may be flushed down the designated waste disposal sink, or dried to a glass in an approved area for site-decay or removal as a solid.

RadioIodination Labs: The most remarkable responses to the value of continual use of I-Bind have come from RadioIodination Labs where containment of volatile, elemental I-125 is a major challenge. The inner surface of the RadioIodination should be sprayed with dilute I-Bind where possible and be allowed to dry to confer protection from the volatile RadioIodine. Please note that every effort must be made to avoid contamination of the iodination vessel, pipets and glassware until the product has been harvested. As soon as possible to be effective all disposable items should be bathed in dilute I-Bind to remove the threat of volatile I125.

Coated RIA tubes can be stripped of their activity after use by soaking in a dilute solution of bleach at first and then by addition of I-Bind to complex the I-125 and prevent iodide gas from forming. Once trapped, the I-125 removed from the coated tubes can be safely flushed down the sewage lines.


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